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8 Additionally, while TMAO affects endothelial barrier function, it can also act on various types of cells, including vascular smooth muscle cells, epithelial cells, pancreatic cells, neurons, astrocytes, microglia, and oligodendrocytes, thereby exerting broad impacts on numerous human diseases

In vitro investigations have highlighted the potential of sulforaphane to prevent the loss of oligodendrocytes and axonal damage in multiple sclerosis, by modulating neuroinflammation and oxidative stress (Morroni et al., 2013

There is research proving that the proliferation of pancreatic cancer cells was greatly inhibited in vitro by PC purified from Spirulina and that the inhibitory effect on the growth of a broad-spectrum cancer cell was enhanced with increasing doses of PC (195)

In a histopathological analysis in mice, the Epi-pledget group showed ameliorated fibrotic changes and necrotic findings in the injured lesion compared with the bipolar coagulation group

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