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First identified in 1973, it has been hypothesized to play a role in tissue repair and regeneration

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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

Unlike products that provide temporary plumping or instant cosmetic effects, GHK-Cu is generally viewed as a long-term skin-support ingredient

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