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In addition to this risk, it is important to highlight that antidepressants such as mirtazapine (especially associated with trazodone), fluoxetine, and nortriptyline have been associated with Clostridium difficile infection in depressed patients [260]

The peptide seems to stimulate the production of nitric oxide, which enhances blood flow and reduces certain forms of inflammation, but it also generates free radicals that damage DNA and proteins