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Studies by our group and others have suggested that locally produced IGF-1 acts in an autocrine/paracrine manner to regulate the proliferation, differentiation, and survival of cell populations that are relevant to the development and maintenance of a healthy skeleton

Furthermore, apart from its antioxidant properties, tocopherol is likely to have a protective effect against heavy metal damage [7,108]

Some of the treatment modalities available, such as chemical peels and prescription skin lightening creams with hydroquinone, are safe and effective for evening out skin tone and eliminating excess hyperpigmentation

[8] Llewellyn died in Chicago of a heart attack on February 13, 1962

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