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doi: 10.1042/bj20100409

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Under physiological conditions, approximately 40% of the total Mn stored in the body is accumulated in bone tissue, as determined in autopsy studies 21,22

In ovarian cancer, increased ROS production and activation of the AKT/mammalian target of rapamycin (mTOR) signaling pathway were involved in the upregulation of SREBP1 and SREBP2, which promoted cell growth and metastasis [55] (Fig