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Not everyone experiences the same reactions to SSRI withdrawal

L-arginine, at a low concentration of 20 mM, has been shown to upregulate Nrf-2 expression, promote its nuclear translocation and enhance the antioxidant capacity of cardiomyocytes (164)

NONMEM user's guide

While it is widely accepted that both the nDNA and mtDNA contribute to the normal function of the mitochondrial ETC, the mechanism underlying cross-talk and communication between these genomes in the diseased state remains under investigation