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Clinical studies suggest that the administration of nutritional supplements, such as docosahexaenoic acid and alpha-lipoic acid, either during the 6 months prior to or concurrently with BTZ treatment, can reduce the onset and progression of BIPN

DNA methylation plays a crucial role in determining the fate of OPCs in health and neurodegenerative diseases Gene expression changes determined by DNA methylation play an important role in the process of lineage specification from OPCs to mature OLGs [68, 105]