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Discussion The mechanism of pancreatic fibrosis in PSCs in chronic inflammation or pancreatic cancer is well known, but studies focusing on the potential role in islet fibrosis and -cell failure are limited [10, 11]

May relate to vasodilation effects

Despite recent advances in the EC research field, cellular and molecular mechanisms driving EC remain poorly understood, largely due to a lack of high-fidelity models that replicate the disease pathology

Ammoniacal nitrogen (NH 3 N) content was measured using phenol-sodium hypochlorite colorimetry, following the Broderick and Kan method (25)

Glutathione is one of the body's most important antioxidants and plays a key role in protecting cells from oxidative stress