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Dietary nitrate is attained from several food sources, such as spinach and beetroot juice ( Meta-analyses by Van De Walle and Vukovich, 2018)

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In this regulatory network, the upregulation of c-MYC , as an important oncogenic transcription factor, not only directly promotes the expression of cell cycle proteins, but also participates in the regulation of cell metabolism, apoptosis, and proliferation, and other aspects of biological processes

doi: 10.3389/fphar.2025.1737199 Received 01 November 2025 Revised 21 December 2025 Accepted 29 December 2025 Published 15 January 2026 Volume 16 - 2025 Edited by Dawei Chen, University of Kiel, Germany Reviewed by Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Updates Copyright 2026 Knudsen, Tadje, Coggins and Venketaraman