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5% due to alternative cytochrome P450 depending glutathione (GSH) conjugation pathway At high doses : Glucuronidation and sulfation pathways become saturated Cytochrome P450 dependent pathway becomes now more important.With depletion of hepatic glutathione, hepatotoxic, reactive, electrophilic metabolites are formed

This may help reduce oxidative stress and improve overall health

The ADAGIO study examined rasagilines disease-modifying effects in a large-scale, double-blind trial

Slow trickle

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