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D-type K+ current rules the function of electrically coupled neurons in a species-specific fashion

For example, 5-HT 1A and 5-Ht 1B agonists inhibit proceptivity and receptivity in Ovx hormonally primed female rats, whereas 5-HT 2 and 5-HT 3 stimulation facilitate lordosis behavior and its antagonism provokes the opposite (Snoeren, 2019)

See the references in these reviews for a more detailed discussion of the history of the identification of the bacterial enzymes for disulphide-bond formation