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Although production was lower compared to glucose (30% for glutarate, 15% for l-2HG), media composition was easy and required only a buffer, a nitrogen source for growth and iron for glutarate hydroxylase

Inhibiting MYCN binding to Myc-associated factor X (MAX) using 10058-F4 (ref

Subnormal GGT activity has been reported to be due to a reduction in the synthesis and release of GGT from hepatocytes resulting in subnormal serum GGT activity

For example, if a patient gets 1000 mcg in 1 mL of 1000 mcg/mL solution, changing to 500 mcg/mL means you need 2 mL to get the same dose

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