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It has been shown that ADC mainly acts on the Nrf2-AREs pathway and scavenges free radicals to exert an ferroptosis inhibitory effect, and ADC may interfere with the Keap1-Nrf2 pathway and activate the Nrf2-AREs pathway (Tan et al., 2021)

FIGURE 1 3 IRP-mediated control of cellular iron metabolism and homeostasis Across the body, the movement of iron into and out of cells must be tightly regulated

cerevisiae , the expression of both GSH1 and GSH2 genes was induced under heat shock treatment (41 C) 34,35

Fortified with alpha lipoic acid, the universal antioxidant that protects against cell damage in a variety of conditions 5

Metabolism-related gene TXNRD1 regulates inflammation and oxidative stress induced by cigarette smoke through the Nrf2/HO-1 pathway in the small airway epithelium