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Its rate of oxidation is accelerated by metal ions such as copper and iron, as well as base (OH ), i.e

Alomran S, Estrella ED

Neurological symptoms can include tingling or numbness in the hands and feet (peripheral neuropathy), a sensation often described as "pins and needles"

doi: 10.1007/s12264-022-00840-x 40 GerberUGeeCEBenquetP

A randomized phase III clinical trial involving 600 early PD patients found no evidence of clinical benefit with high-dose CoQ 10 (1200 mg/d and 2400 mg/d) supplementation (207)