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this will in turn influence the function of governing the free flow of qi by the liver, and thus, induce distension/pain in the subcostal region, abdominal distension, nausea, vomiting, a bitter taste, poor appetite, and jaundice

Biochem Pharmacol 67(1):7785

The best known cellular function of p62 is as a selective autophagy receptor (Pankiv et al., 2007

Once water-soluble, these neutralized toxins can be safely and efficiently excreted from the body through bile and urine

Budget-conscious approach: If you can only afford a few tests, prioritize in this order: HbA1c + fasting glucose + fasting insulin (about $30-50 direct) Lipase (about $15-25 your critical safety marker) Lipid panel + liver enzymes (usually bundled for $25-40) Calcitonin (about $30-50 baseline at minimum) Putting It All Together: Sample Protocol Week -1 (Baseline): Run HbA1c, fasting glucose, fasting insulin, lipid panel, liver enzymes (ALT, AST, GGT), lipase, amylase, TSH, free T4, calcitonin, CBC, CMP