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RAS RAS is the first oncogene implicated in ferroptosis, with erastin and RSL3 initially identified through a RAS synthetic lethal screen

Figure 1 3.3 Chromosomal location and collinearity analysis of VcGST genes Vaccinium corymbosum Draper is a tetraploid species with 48 chromosomes (2n = 4x = 48)

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An example of an approved therapy is Venetoclax, a BCL2 inhibitor which has demonstrated efficacy as a monotherapy or in combination regimens for treating chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML) (1517)