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As a representative bitter-cold purgative medicinal herb, Rhubarb has many bioactive components that exhibit diverse pharmacological effects, such as antioxidant, lipid-regulating, and anti-inflammatory effects [128]

Immunofluorescence analysis confirmed that the RhoA-GTP signal is concentrated at mature IDs of WT mouse heart sections (Fig 4B and insets)

This may be useful among patients who require long-term intubation

Histopathological analysis was evaluated by a three-grade system for synovitis (inflammation), cartilage destruction and bone erosion as previously described 54 , five sections for each animal