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Al-Hadrawi DS, Al-Rubaye HT, Almulla AF, Al-Hakeim HK, Maes MF

Additionally, ROS-induced AhR signaling can either activate the NLRP3 inflammasome, 211 or inhibit macrophage pyroptosis by upregulating ornithine decarboxylase 1 (Odc-1), enhancing polyamine biosynthesis (e.g., spermine), which suppresses K + efflux and inflammasome assembly, as observed in ulcerative colitis patients 212 (Fig

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Neurobiol Dis 37(2):434440

Kahaly GJ, Bartalena L, Hegeds L, Leenhardt L, Poppe K, Pearce SH