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The use of both trypsin and pepsin as proteases was shown to be complementary

10.1007/s00217-018-3076-6 74 LiH.TangY.LiuZ.ChenK.ZhangK.HuS.et al (2024)

This is because the body may start to break down collagen and muscles for fuel because of lower energy levels

doi: 10.1152/ajpcell.00040.2005

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