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Low SHBG symptoms are those that present with high testosterone 18 or estrogen, such as: Excessive facial and body hair (hirsutism) Acne Irregular or missing periods Thinning hair Weight gain Mood swings Causes of Low SHBG Similar to high SHBG, some of these may or may not be causes, but may be associated with a health condition: Hypothyroid : Just as hyperthyroid can contribute to high SHBG, hypothyroidwhen the body doesn't make enough thyroid hormonecan cause low SHBG 19 levels

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CrossRef Exocarpium Citri Grandis alleviates postmenopausal obesity in ovariectomized mice through gut microbiota remodeling and metabolic reprogramming Tingting Chen, Xiaoqin Wu, Like Xu, Jiaxiong Zhao, Weiru Liu, Jiangtao Zeng, Zhuohui Luo, Jiawen Huang Journal of Functional Foods.2025