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A national assessment of T2 staging for intrahepatic cholangiocarcinoma and the poor prognosis associated with multifocality

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Similarly, Cys undergoes rapid oxidation to its disulfide moiety upon delivery, thereby generating an inactive disulfide cystine (Cys-Cys), and due to its poor solubility, the sulfhydryl functional group on Cys is rendered temporarily inaccessible [28]

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74 There was a reduction in the Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBO) score from a mean of 20.3 at baseline to 11.8 at the end of an 8-week open-label phase where participants received NAC, starting with 600 mg per day and increasing to up to 1800 mg per day, depending on their response