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There is evidence that ZIP6 is negatively correlated with EMT

Biochemistry (1985) 24(15):39225

Yirmiya R, Rimmerman N, Reshef R (2015) Depression as a microglial disease

It is unclear whether this observation was due to the effects of time-restricted feeding (ie, intermittent fasting), a lower overall caloric intake with once-daily feeding (ie, caloric restriction), or whether pre-existing health conditions in the dogs may have affected how frequently they were fed