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In any case, TRP channels are now presented as attractive targets for the development of new-generation analgesics

& Sung, J

The first site interacts with the glutathione moiety of glutathionylated disulfide substrates

Overexpressing of FZD7 activates the oncogenic factor tumor protein 63 (TP63), leading to increased levels of glutathione metabolic pathways, including GPX4, which protects cells against chemotherapy-induced oxidative stress and ferroptosis