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Long term use may lead to serious complications such as stomach bleeding and kidney problems

Overproduction of insulin can affect astrocytes and A accumulation by saturating insulin-degrading enzyme (IDE), which was also found to degrade A (Kang et al., 2017)

Montagner, A., et al

doi: 10.3390/antiox10040526 39 MittalMGuXQPakOPamenterMEHaagDFuchsDBet al

For mitochondria, the intensity image was first smoothed with a mean filter (radius = 2.0 pixels) and then processed with a separate pre-trained Weka classifier (200 trees, 2 features per split)