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Long-term wine consumption is related tocardiovascular mortality and life expectancy independently of moderate alcohol intake: the Zutphen Study

Hoeijmakers JG, Faber CG, Lauria G, Merkies IS, Waxman SG

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The activation of the immune system against gluten peptides begins after their transfer to the lamina propria where they are deamidated by the tissue transglutaminase enzyme and subsequently bounded to human leucocyte antigens (HLAs) expressed by antigen-presenting cells (APCs), which activate the inflammatory cascade (Figure 2) (239, 240)

Genes producing signalling peptides with positive cognition coefficients exhibited enrichment within inhibitory interneurons (INs), namely VGF, SST and TAC1 (Fig