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These effects were not reproduced in 3-AR knockout mice, suggesting that the 3-AR plays a key role in the compounds chronic metabolic effects (Heffernan et al

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In NSCLC, Alimta is approved for various settings, including initial treatment in combination with cisplatin for locally advanced or metastatic non-squamous NSCLC, as maintenance therapy after initial chemotherapy, and as a single agent for patients with locally advanced or metastatic non-squamous NSCLC after prior chemotherapy

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[DOI] [PMC free article] [PubMed] [Google Scholar] Wang J