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In 1994, Mizuno et al

It is estimated that PD affects at least 1% of the population over the age of 60 (Zafar and Yaddanapudi, 2023)

p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-Driven Gene Transcription

We collected laboratory data (AST, ALT, PLT, and MCV) as well as liver stiffness (by VCTE) when available

Although melasma is a non-malignant skin disorder, however, if a proper, well-timed, and optimum therapeutic regimen is not considered, it can induce various psychological and emotional distress including feelings of frustration, unattractiveness, and embarrassment (Wu et al., 2021)