5-amino-1mq nnmt inhibitor studies

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[13] In the setting of acute isoniazid overdose or toxicity, extraordinarily high doses of pyridoxine are used as an antidote: the recommended approach is to administer pyridoxine in a total amount equal to the amount of isoniazid ingested

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Imai S

Second, NNMT depletes that universal methyl donor, SAM, which is essential for DNA methylation, neurotransmitter production, and other indispensable biological processes