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This harmful effect was not limited to the summer season, as it continued until autumn, indicating a carry-over effect caused by heat stress during the summer

Altered cytokine endotoxin responses in neonatal encephalopathy predict MRI outcomes

doi:10.3389/fneur.2020.570989

Importantly, many of the age-related alterations described above converge on a common endocrine signal: melatonin

The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension