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This is done while the patient is awake in the office, under a local anaesthetic

Recent studies have elucidated potential mechanisms of chemotherapy-induced ovarian damage, including DNA damage, oxidative stress, mitochondrial dysfunction, and apoptotic signalling abnormalities induced by cisplatin and other chemotherapeutic agents (8, 9)

Tell your clinician about all medicines and supplements you take to reduce interaction risks

After 48 h, cells were pelleted at 2000 g and resuspended in breaking buffer (50 mM sodium phosphate, 5% glycerol, 1 mM EDTA, pH 7.4) and frozen prior to processing

3c and 4c and Extended Data Figs