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This epigenetic intervention engages in extensive cross-talk, potentially through global demethylation and modulation of microRNA expression, thereby reversing aberrant gene transcription profiles in cancer (65)

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Chronic activation of the JAK/STAT pathway results in sustained inflammation, creating a feedback loop that prevents effective tissue repair and exacerbates urothelial damage (Peskar et al., 2023)

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High homocysteine levels are associated with reduced fertility in many ways including, poor oocyte quality, miscarriage, hypertension, and low birth weight