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However, it was not ruled out that tubular cell death might have occurred secondary to some changes outside the tubular compartment: e.g., in RIPK3-dependent organ perfusion, which might be altered also upon Nec-1 treatment if the necroptotic pathway was involved

[DOI] [PubMed] [Google Scholar] 183.Sharon G., Sampson T.R., Geschwind D.H., Mazmanian S.K