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The loss of insulin sensitivity of hippocampal CA1 pyramidal neurons can subsequently cause long-term Ca 2+ -dependent afterhyperpolarizations (AHPs), which can produce significant cognitive and memory impairment in the short term and throughout life, contributing to depression (122, 123)

The LDH reaction solution (100 L) was added with subsequent incubation at room temperature away from light for 30 min

Wang, S., Furchtgott, L., Huang, K

Understanding how altered BDNF-TrkB signaling, particularly in iSPNs, might lead to early dopamine dysfunction in Huntington's disease could provide targets for potential preventative therapy

In this case, the function of Hb is disturbed, the oxygen supply decreases and finally, hypoxia increases