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These pilot and phase I study results motivate larger, longer-duration phase II clinical trials that test the efficacy of intravenous ascorbic acid in disease progression and overall survival

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Arch Toxicol 89:193199 Liu YT, Chen YH, Uramaru N, Lin AH, Yang HT, Lii CK, Yao HT (2016) Soy isoflavones reduce acetaminophen-induced liver injury by inhibiting cytochrome P-450-mediated bioactivation and glutathione depletion and increasing urinary drug excretion in rats

This mechanism is conservatively expressed in colorectal cancer, bladder cancer, and acute myeloid leukemia, constituting an essential metabolic foundation for the rapid proliferation of tumor cells