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6 Targeting ROS or mitochondria in RA therapy drugs 6.1 Inhibition of inflammation Inhibition of inflammatory response is critical in the course of RA treatment, and biological agents, such as TNF- monoclonal antibodies, IL-6 monoclonal antibodies, and JAK pathway inhibitors, have been developed for inflammatory factors and have achieved significant clinical efficacy

Every 250 ml of green tea beverage contains 240320 mg of catechins, most of which (6065 %) is epigallocatechin gallate (Reference Balentine, Wiseman and Bouwens49,Reference Sang, Lambert and Ho50)

Wang K, Kai L, Zhang K et al (2020) Overexpression of phzM contributes to much more production of pyocyanin converted from phenazine-1-carboxylic acid in the absence of RpoS in Pseudomonas aeruginosa

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