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Participants were asked to exert the established force (50% of the individual baseline maximum capacity MVC force) on a hand dynamometer (TSD121B-MRI, Biopac) within a specific timeframe (e.g., 2 seconds) and sustain it for 3 seconds after

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Iron metabolic pathways and ferritin phagocytosis are two key factors that regulate ferroptosis (15)

Given the short duration of the study, no interim analysis was planned, and no stopping rule was predefined