Side Effects & Safety Mild GI discomfort most common, usually transient in the first week Slight stimulant effect increased energy/alertness, especially early on Headaches occasional, typically mild and dose-related Mild insomnia if taken too late in the day No human clinical safety data all safety information from preclinical studies and community reports No liver toxicity observed in animal studies at therapeutic doses Unknown drug interactions theoretically could interact with NAD+-dependent pathways Core Supplies for This Protocol The three essentials for running any reconstituted injectable: cold storage, accurate syringes, and metabolic tracking

Some high risk groups for vitamin B12 deficiency include: elderly people- often stomach acid production decreases with age individuals who have had intestinal surgery such as weight loss surgery or laparoscopies individuals with GI issues including celiac disease, IBD, IBS (MOST OF YOU!!!) those following a vegetarian or vegan diet- due to the lack of animal protein eaten (one of the main sources of B12) individuals with pernicious anemia- do not make intrinsic factor Notice how a fair amount of the high risk individuals are those with some sort of intestinal issue
All of these factors may contribute to increased demands for B vitamins
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When picking a B12 formulation, its key to think about the patients specific needs and any possible interactions with other drugs