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Circadian rhythm generation and entrainment in astrocytes

Abstract Splicing of precursor messenger RNA (pre-mRNA) in eukaryotic cells is carried out by the spliceosome 1 , which consists of five small nuclear ribonucleoproteins (snRNPs) and a number of accessory factors and enzymes 2

M.ParkC

Health economics Older adults living with severe obesity have increased healthcare use and cost [22], although the effect of obesity on years-of-life-lost is greatest in younger adults, and the magnitude of years lost with obesity decreases with ageing [16], irrespective of sex, smoking status, physical activity level, or socioeconomic status [35], complicating the health economic considerations of obesity management in older adults