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At body temperature cystine which is released from protein diet interacts with allicin in gastrointestinal tract (GI) tract to generate two S-allylmercaptocysteine (SAMC) derivatives (113)

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By combining h-HepOrgs with portal mesenchyme and our previously published cholangiocyte organoids 4,5,6 , we generated patient-specific periportal liver assembloids that retain the histological arrangement, gene expression and cell interactions of periportal liver tissue, with cholangiocytes and mesenchyme embedded in the hepatocyte parenchyma

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