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We find that ROS production correlates to a binding mode where two imidazole nitrogen atoms coordinate to the copper-ion leaving the remaining binding sites free for interaction with e.g

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Mutat Res Fund Mol Mech Mutagen

There were no significant differences in oxidative stress biomarkers between the psoriasis group and the AD group, except for increased CAT activity in the AD group ( p 2,000 IU/day (79)