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Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimers disease

Unapproved peptide products, particularly those that are injected, carry significant safety risks, including contamination, infection or local tissue damage

This process reduces endothelial junction protein expression, thereby mitigating albumin leakage from endothelial cells and reducing white blood cell infiltration after I/R, which alleviates cellular edema and enhances coronary vascular endothelial barrier integrity, as well as minimizing microvascular leakage (He et al., 2022)

(2022) 53:e13895

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