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In macrophages, where inflammatory responses have been studied in more detail, NOD2 induces production of IL6, TNF, CXCL1, and chemokine (C-C motif) ligand 2 (CCL2) [39]

Figure 3 Figure 4 2.1.4 Ferroptosis and necroinflammation Cellular ferroptosis triggers the innate immune system by releasing damage-associated molecules associated with inflammation

Flavonoids such as quercetin and naringenin have significant ROS scavenging abilities, which help protect neuronal cells from oxidative damage ( 4.3 Inhibition of inflammation Natural products often possess anti-inflammatory properties that complement their antioxidant effects