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These enzymes may play critical roles in detoxifying reactive oxygen species, thereby protecting the cell from oxidative damage

To get the most from B12 therapy, following a good maintenance plan is key

2.1 Literature search A systematic search of the PubMed, EMBASE, Cochrane Library, Web of Science, and CNKI databases for relevant observational studies published until 15 March, 2022, was undertaken independently by two reviewers (Zhao and Li)