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"Just how grateful we are for the incredible support from our colleagues and campus partners

ROS, due to unpaired electrons, have strong oxidative potential and can damage cellular DNA and proteins (Guo et al

Chih, B., Engelman, H

Although AVE significantly alleviated MMS-induced toxicity, some residual damage persisted, suggesting that it cannot completely counteract genotoxic stress at the tested concentrations

Protein samples aliquots were prepared as described in the 2D Clean-up Kit (GE Healthcare Life Science, USA), and the pellet of the final step was solubilized in sample buffer containing 7 M urea, 2 M thiourea, 40 mM Tris (0.5 M, pH 8.5), 4% CHAPS, 65 mM DTT, and 1% IPG buffer