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Additionally, the study design does not allow for evaluating the impact of various DMTs on the levels of examined parameters

These enzymes are iron dependent (115118): Their catalytic activity is suppressed when iron deficiency is present, causing phagocytosis to be impaired

So if there's a possibility to reduce down the oxidative stress to bare minimum, it can never be zero because you need to have limited oxidative stress for the body to stay focused and more resilient