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The hydrated form of cisplatin cross-links with nucleotides of nuclear and mitochondrial DNA to form adducts, inhibiting the indefinite replication of cancer cells 1,2

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF et al (2011) Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets

Am J Hematol 96:E38E40

9.2 Mitochondrial targeted antioxidants 9.2.1 MitoQ MitoQ is a specialized antioxidant designed to specifically target the mitochondria in the context of Alzheimer's disease (AD)