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10.1186/s12931-016-0500-y Respir Res

However, following administration of the ferroptosis inhibitors liproxstatin-1 or ferrostatin-1, the levels of inflammatory factors and ROS are reduced, endogenous antioxidant pathways related to Nrf2, HO-1, and NQO1 are upregulated, transforming growth factor- expression is downregulated, and iron ptosis is reduced in lung tissue [107]

doi: 10.2337/diab.46.11.1733

Biochemical analysis showed an increase in total antioxidant capacity (TAC) and a decrease in malondialdehyde (MDA) and high-sensitivity C-reactive protein (hs-CRP) levels when compared with baseline measurements

COMT o-methylates catechol oestrogen metabolites and mediates their detoxification, and it is plausible that the activity of this enzyme is inhibited by the accumulation of the cysteine precursor homocysteine