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doi: 10.3389/fnins.2023.1087788 147 HendersonCWijetungeLKinoshitaMNShumwayMHammondRSPostmaFRet al

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Searching for novel candidate small molecules for ameliorating idiopathic pulmonary fibrosis: a narrative review

A 8 mL of tube was charged with 3-bromo-5-(difluoromethoxy)-2-methylpyridine (330 mg, 1.386 mmol), 4,4,4,4,5,5,5,5-octamethyl-2,2-bi(1,3,2-dioxaborolane) (528 mg, 2.080 mmol), potassium acetate (408 mg, 4.16 mmol), PdCl 2 (dppf) (101 mg, 0.139 mmol) and 1,4-Dioxane (3 mL) at 25 C

This significantly reduces liver function, and may progress to liver failure and death (1)