does oxidation state of glutathione depends on cysteine residue Frontiers Glutathione in Protein Redox Modulation

AGEs not only react with biomolecules such as proteins and lipids but also exacerbate oxidative stress, impairing the energy metabolism of cardiomyocytes and ultimately leading to cardiac dysfunction (84)

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for the GHK-Cu complex, the apo form is GHK itself