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BRD4 Proteolysis Targeting Chimera (PROTAC) Leads to Sustained Degradation of BRD4 with Broad Activity Against Acute Leukemias and Overcomes Stroma Mediated Resistance by Modulating Surface Expression of CXCR4

Of note, psoriasis shares striking similarities with atherosclerosis, such as the histological features and a immunoinflammatory cascade involving Th1, Th17, Tregs, and downstream expression of cytokines [70]